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Targeting the Non-Canonical NF-κB Pathway in Chronic Lymphocytic Leukemia and Multiple Myeloma
This study was designed to investigate the potential for targeting the NF-kB inducing kinase, NIK, in two common B-cell malignancies, …
Burley TA
,
Kennedy E
,
Broad G
,
Boyd M
,
Li D
,
Woo T
,
West C
,
Ladikou EE
,
Ashworth I
,
Fegan C
,
Johnston R
,
Mitchell S
,
Mackay SP
,
Pepper AGS
DOI
TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target
Chronic lymphocytic leukemia (CLL) remains incurable despite B-cell receptor-targeted inhibitors revolutionizing treatment. This …
Emma Kennedy
,
Eve Coulter
,
Emma Halliwell
,
Nuria Profitos-Peleja
,
Elisabeth Walsby
,
Barnaby Clark
,
Elizabeth H Phillips
,
Tom Burley
,
Simon Mitchell
,
Stephen Devereux
,
Christopher D Fegan
,
Christopher I Jones
,
Rosalynd Johnston
,
Tim Chevassut
,
Ralph Schulz
,
Martina Seiffert
,
Angelo Agathanggelou
,
Ceri Oldreive
,
Nicholas Davies
,
Tatjana Stankovic
,
Triantafillos Liloglou
,
Chris Pepper
,
Andrea Pepper
DOI
Combined analysis of IGHV mutations, telomere length and CD49d identifies long-term progression-free survivors in TP53 wild-type CLL treated with FCR-based therapies
Combined analyses of the pairs of biomarkers A IGHV mutation status and CD49d, B IGHV mutation status and telomere length and C …
Andrea Pepper
,
Antonella Zucchetto
,
Kevin Norris
,
Erika Tissino
,
Jerry Polesel
,
Zarni Soe
,
David Allsup
,
Anna Hockaday
,
Pei Loo Ow
,
Peter Hillmen
,
Andrew Rawstron
,
Daniel Catovsky
,
Pietro Bulian
,
Riccardo Bomben
,
Duncan M Baird
,
Christopher D Fegan
,
Valter Gattei
,
Chris Pepper
DOI
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